Quality of Skin Care Products.


How can we improve the quality of Skin care products? What are the Critical Quality Attributes (CQAs) associated with Skin care products? How can these be eliminated or minimised?

Skin Care Products
Cream/Ointment manufacturing/equipment/Tech Transfer
Semisolid dosage forms
Pharmaceutical Manufacturing
FDA regulations
Critical Quality Attributes (CQA)
Quality Target Product Profile (QTPP)
Formulation Development
Formulation of Cosmetics/Skincare Products
Formulation Science
Formulation Chemistry
Abhishek Raj
78 months ago

2 answers


Challenges is what is covered by insurance and what is patient pay-
although people undedstand that dematogical procedure can likely be classified as cosmetic and fall directly to patient it is always the hope as many skin conditions although may apear cosmetic in nature in essence truly havr a medical componet, should be treated by a HCP, and thus should be reimbursed accordingly.

Tricia Sterling
78 months ago
Dear Tricia, Thank you for your answer. You are right people often consider all skin care products as cosmetics but this is not true in case of medicated skin care products and their potency and efficacy is very important as well as the product stability is crucial. How can we improve these to give a quality product to end users? - Abhishek 78 months ago
Well explained - Dr. David E. 63 months ago

Skin care market can be devided into (i) Female skin care & (ii) Male skin care. Although women embrace skin care as a part of general health, this concept has not gained wide male acceptance. There are many physiologic differences between male and female skin, with less of a need for moisturization and photoprotection in men. Therefore, male, and female skin care products require different products attributes. In addition, the product attributes requirement is also different for different kinds of skin types. The product attributes vary from format to format, e.g. cream over gel or vice versa. The major attributes consumers talk about in skin care products are (i) Easy to apply/use/spread, (ii) Easy to use on hair-bearing skin, (iii) comfortable to use under makeup and/or cosmetics, (iv) suitable for use on multiple body areas, (v) Stain free, (vi) Soothing, (vii) Did not dry the skin, (viii) Disappeared quickly, (ix) comfortable to wear under clothes, and was not greasy or shiny on skin. The product is suitable for sensitive skins i.e. it should not irritate skin. And finally, the product should provide desired benefits.

The properties of vehicle formulations may influence drug delivery, efficacy, and tolerance profiles of topical medications. Patient preferences vary, and the importance of certain aesthetic attributes depend on the disease state, the site of application, and the length and extent of treatment, among other factors. Formulations that offer aesthetic advantages over traditional vehicles may improve patients' willingness to apply therapy as directed and therefore may affect the outcome of treatment. These vehicles come in different formats such as gels, creams, lotions, and foams; some ingredients are common to many vehicles, while some vehicles contain unique ingredients designed to optimize skin penetration and delivery of the active drug to its target. Vehicles can also influence tolerability, which is always a concern in patients with skin sensitivity, and compliance. Ideally, the vehicle of any skin care product should enhance drug delivery, be nonirritating and be easy to use. Ingredients that help repair barrier function are also desirable. Therefore, the vehicle used in any skin care formulations influence the delivery of active ingredient, skin barrier repair, tolerability, and compliance.

The entire skin care range of products can be classified into two major group, 
(i) Cosmetics & (ii) OTC
Different regulatory principles govern each category. 

Samares B
76 months ago
Dear Samares, Thank you for your answer. You said entire skin care products can be classified as cosmetics and OTC. What about prescription (Rx Products)? Also what are the challenges during formulation of skin care products and how can they be minimised? - Abhishek 76 months ago

Have some input?