menu

Advance cardiovascular risk stratification

0
692 views

Why is standard lipid testing still the gold standard for risk stratification when better, more predictive biomarkers are available?

Lipid Disorders
Particle Size Analysis
Risk Factor Analysis
Kenneth Johnson MD, MBA FACC
19 months ago

2 answers

0

Lipid profiling is commonly followed for the routine evaluation because of the high correlations of hypercholesterolemia and hypertriglyceridemia and CVD. Also, the cost for other biomarker testing makes lipid profiling a better, robust and most economical approach cor risk stratification.

Sandeep Varma
19 months ago
0

Cardiovascular disease (CVD) is the results of complex combinations of multiple factors and there is no single risk factor has been taken as the main factor for distinguishing people who will go on to develop a cardiovascular event from those who will not. Combinations of all the factors leads to CVD risk assessment and prediction model.
As a part of protocols lipid profile measures multiple factors that are directly related to multiple heart disease conditions and forms the essential part for diagnosing and predicting CVD. There are other modern biomarkers and testing methods medical practitioners use for additional supporting data for prediction model. As Sandeep rightly pointed out, all these additional test sometime very costly.

References:
Heart Lung Circ. 2018, 27(1):79-88.
PLoS One. 2018, 13(1):e0190441.
Sci Rep. 2017, 7(1):17552.
J Cardiovasc Med (Hagerstown). 2017, 18(5):318-324.
Cardiovasc J Afr. 2013, 24(9): 376–381.
Health Technol Assess. 205, 19(100):1-401
Regul Toxicol Pharmacol. 2013, 65(1):38-46.
Eur J Cardiovasc Prev Rehabil. 2009,16(5):562-70


The following picture is taken from http://www.acc.org/latest-in-cardiology/articles/2014/08/25/15/07/advanced-lipoprotein-testing-strengths-and-limitations


Samares B
19 months ago

Have some input?