not exactly the answer I think you are looking for but i hate when people send resumes that look like infographics or have lots of unnecessary and distracting fonts/colors/shapes etc. Your skills and experience should speak for themselves.

The most irrelevant thing i have always noticed is "Career Objective" Its there mostly in resumes of fresh graduates or 1-2 years of experience but hardly anyone ever write it in understandable manner. Keeping a opening line on your resume which will look like copy-paste really piss-off anyone reading that resume. I seen most absurd language in the Career objective sections of resume.

Hobbies.
I have reviewed thousands of resumes and occasionally one comes across with an entire section, replete with bold and underline to signify the new heading, to discuss their completely unrelated hobby,
I can understand if someone were to include a hobby if it is directly related to the position, industry or field in which they are applying. I would want to see Amateur Drone Racing League organizer and competitor if I am seeking a skilled drone operator for camera work. I would not want to see a hobby of ornithology on a resume applying for a role as Systems Engineer. Use that space to express your potential value to the company, or your ongoing professional development efforts. Should we end up meeting for an interview and you feel it is appropriate to discuss the silver throated swallow that perched on the window sill please do, but putting in on a resume is wasting valuable page space. In my opinion.

Good question, and when I see some irrelevant things, it makes me think about the personality of the candidate. The areas which I feel are irrelevant on resume are :
Hobbies, Personal Interests, Lengthy sentences, Grammatical mistakes.
People need to keep their CV's short and precise.